General information
| PDB ID | 2X2C |
|---|---|
| Chain ID | B;F;L;P;R |
| Length | 11 |
| Peptide type | Non-natural |
| Complex | Complex |
| Peptide name | CYCLOSPORIN A |
| Source organism | Tolypocladium Inflatum |
| Experimental method | X-RAY DIFFRACTION |
| Release | 2010-03-23 |
Sequence & modifications
| Sequence | ALLVTAGLVLA;MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE;;; |
|---|---|
| Nonstandard residue | DAL,MLE,MVA,BMT,ABA,SAR,ALY |
| Modified sequence | (DAL)(DAL)(MLE)(MLE)(MLE)(MLE)(MVA)(MVA)(BMT)(BMT)(ABA)(ABA)(SAR)(SAR)(MLE)(MLE)VV(MLE)(MLE)AA;(DAL)M(MLE)V(MLE)N(MVA)P(BMT)T(ABA)V(SAR)F(MLE)FVD(MLE)IAAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDG(ALY)HVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE;(DAL)(MLE)(MLE)(MVA)(BMT)(ABA)(SAR)(MLE)V(MLE)A;(DAL)(MLE)(MLE)(MVA)(BMT)(ABA)(SAR)(MLE)V(MLE)A;(DAL)(MLE)(MLE)(MVA)(BMT)(ABA)(SAR)(MLE)V(MLE)A |
Structure information
| Disulfide number | - |
|---|---|
| Disulfide position | - |
| Cyclization type | H2T |
| Structure feature | Coil |
| Ring number | 1 |
3D visualization
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Literature information
- PubMed: 20364129
- DOI: 10.1038/NCHEMBIO.342
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